Engineering 3D Cortical Spheroids for an In Vitro Ischemic Stroke Model

Three-dimensional (3D) spheroids composed of brain cells have shown great potential to mimic the pathophysiology of the brain. However, a 3D spheroidal brain-disease model for cerebral ischemia has not been reported. This study investigated an ultralow attachment (ULA) surface-mediated formation of...

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Veröffentlicht in:ACS biomaterials science & engineering 2021-08, Vol.7 (8), p.3845-3860
Hauptverfasser: Ko, Eunmin, Poon, Mong Lung Steve, Park, Eunyoung, Cho, Youngbin, Shin, Jennifer H
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Sprache:eng
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