Mirtazapine-induced decrease in cocaine sensitization is enhanced by environmental enrichment in rats

Several studies have reported that mirtazapine attenuated the induction and expression of cocaine-induced locomotor sensitization. Animals placed in enriched housing environments have shown a decrease in cocaine-induced locomotor activity and sensitization. In addition, it has been suggested that a...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2021-09, Vol.208, p.173237-173237, Article 173237
Hauptverfasser:	Barbosa-Méndez, Susana, López-Morado, Casandra, Salazar-Juárez, Alberto
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressant Antidepressive Agents - pharmacology Behavior, Animal - drug effects Cocaine Cocaine - administration & dosage Cocaine - pharmacology Cocaine-Related Disorders - drug therapy Cocaine-Related Disorders - metabolism Dopamine Uptake Inhibitors - pharmacology Enriched environment Environment Housing, Animal Locomotion - drug effects Locomotor sensitization Male Mirtazapine Mirtazapine - administration & dosage Mirtazapine - pharmacology Pharmacotherapies Rats Rats, Wistar Substance Withdrawal Syndrome - drug therapy Substance Withdrawal Syndrome - metabolism
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