Exploration of the Antimicrobial Effects of Benzothiazolylthiazolidin-4-One and In Silico Mechanistic Investigation

Background: Infectious diseases still affect large populations causing significant morbidity and mortality. Bacterial and fungal infections for centuries were the main factors of death and disability of millions of humans. Despite the progress in the control of infectious diseases, the appearance of...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2021-07, Vol.26 (13), p.4061, Article 4061
Hauptverfasser:	Haroun, Michelyne, Tratrat, Christophe, Petrou, Anthi, Geronikaki, Athina, Ivanov, Marija, Ciric, Ana, Sokovie, Marina, Nagaraja, Sreeharsha, Venugopala, Katharigatta Narayanaswamy, Nair, Anroop Balachandran, Elsewedy, Heba S., Kochkar, Hafedh
Format:	Artikel
Sprache:	eng
Schlagworte:	Ampicillin Anti-Infective Agents - chemical synthesis Anti-Infective Agents - pharmacology antibacterial Antibacterial activity Antimicrobial agents Bacterial Proteins - antagonists & inhibitors Bacterial Proteins - chemistry Bacterial Proteins - metabolism Benzothiazole Biochemistry & Molecular Biology Carbon Carboxypeptidase Carboxypeptidases - antagonists & inhibitors Carboxypeptidases - chemistry Carboxypeptidases - metabolism Chemistry Chemistry, Multidisciplinary Design docking Drug development Drug resistance Drugs E coli Enzymes Hydrocarbons Infectious diseases Kinases LD-carboxypeptidase Life Sciences & Biomedicine Listeria monocytogenes - drug effects Methicillin-Resistant Staphylococcus aureus - drug effects MIC/MFC Minimum inhibitory concentration Molecular Docking Simulation Morbidity PASS Physical Sciences Protease Inhibitors - chemical synthesis Protease Inhibitors - pharmacology Public health Salmonella typhimurium - drug effects Science & Technology Software Strains (organisms) Streptomycin Thiazolidines - chemical synthesis Thiazolidines - pharmacology thiazolidinones
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