Liposome-encapsulated methemoglobin as an antidote against cyanide poisoning

Cyanide induces acute lethal poisoning resulting from inhibition of cytochrome c oxidase located in the complex IV (Complex IV) of mitochondria. However, current therapies for cyanide poisoning using hydroxocobalamin and nitrous acid compounds remain a clinical issue. Here, we show that liposome-enc...

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Veröffentlicht in:	Journal of controlled release 2021-09, Vol.337, p.59-70
Hauptverfasser:	Suzuki, Yuto, Taguchi, Kazuaki, Kure, Tomoko, Sakai, Hiromi, Enoki, Yuki, Otagiri, Masaki, Matsumoto, Kazuaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomimetics Cyanide poisoning Liposome Methemoglobin Red blood cells
Online-Zugang:	Volltext
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