Carboxymethylated and acetylated xerogel derivatives of Plectranthus esculentus starch protect Newcastle disease vaccines against cold chain failure

•Starch derivatives kept Newcastle disease vaccine stable in cold chain failure.•Stability of these vaccines was 4–6 times better than peptone stabilized vaccine.•Vaccinated chickens developed high serum antibody levels after a single dose.•Vaccines fortified with starch derivatives were stable and...

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Veröffentlicht in:	Vaccine 2021-08, Vol.39 (34), p.4871-4884
Hauptverfasser:	Guktur, R.E., Nep, E.I., Asala, O., Olorunfemi, P.O, Ngwuluka, N.C., Ochekpe, N.A., Sagay, A.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Acetylation/xerogel Ambient temperature Antibodies Antibody Antigens Buffers Carboxymethylation Cold Cold chain failure Disease Dosage Embryos Epidemics Evaluation Freeze-dried Hemagglutination inhibition Immunogenicity Immunology Laboratories Life Sciences & Biomedicine Mannitol Medicine, Research & Experimental Moisture content Newcastle disease Oral administration Peptones pH effects Plectranthus esculentus Poultry Power supply Proteins Research & Experimental Medicine Science & Technology Sodium Sodium hydrogen phosphate Stability analysis Stabilizer Starch Starches Supply chains Trehalose Tubers Vaccine Vaccines Viruses Water content Xerogels
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