Differentially expressed microRNA in testicular tissues of hyperuricaemia rats

Differentially expressed microRNA in testicular tissues of hyperuricaemia rats

This study is to identify the differentially expressed miRNAs in testicular tissues of rats with hyperuricaemia‐induced male infertility. We found that the hyperuricaemia model group had significantly increased serum uric acid, while significantly decreased sperm concentration and motile sperm perce...

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Veröffentlicht in:ANDROLOGIA 2021-11, Vol.53 (10), p.e14184-n/a, Article 14184
Hauptverfasser: Ma, Jing, Han, Ruiyu, Sun, Bo, Lin, Jiajie, Deng, Peipei, Wang, Shusong, Sun, Shaoguang
Format: Artikel
Sprache:eng
Schlagworte:
3' Untranslated regions
Andrology
Animals
Calcium signalling
Endocrinology & Metabolism
Gene Expression Profiling
hyperuricaemia
Hyperuricemia
Hyperuricemia - genetics
Infertility
Life Sciences & Biomedicine
Male
MAP kinase
microRNA
MicroRNAs - genetics
miRNA
Rats
RNA, Messenger
Science & Technology
Signal Transduction
Sperm
spermatozoa
Testes
testicle
Testis
TOR protein
Uric Acid
Wnt protein
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Zusammenfassung:This study is to identify the differentially expressed miRNAs in testicular tissues of rats with hyperuricaemia‐induced male infertility. We found that the hyperuricaemia model group had significantly increased serum uric acid, while significantly decreased sperm concentration and motile sperm percentage than normal group (p 
ISSN:0303-4569
1439-0272
DOI:10.1111/and.14184