Partial Consensus Design and Enhancement of Protein Function by Secondary-Structure-Guided Consensus Mutations

Consensus design (CD) is a representative sequence-based protein design method that enables the design of highly functional proteins by analyzing vast amounts of protein sequence data. This study proposes a partial consensus design (PCD) of a protein as a derivative approach of CD. The method replac...

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Veröffentlicht in:	Biochemistry (Easton) 2021-07, Vol.60 (29), p.2309-2319
Hauptverfasser:	Kozuka, Kohei, Nakano, Shogo, Asano, Yasuhisa, Ito, Sohei
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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