Neurochemical and behavioral effects of lorazepam: A dose related study

Present study was designed to monitor the dose dependent effects of lorazepam; a benzodiazepine (CNS depressant). It is the primary drug of choice for treatment of anxiety and to produce calming effects. However, repeated administration of this lorazepam causes dependence and this might be caused by...

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Veröffentlicht in:	Pakistan journal of pharmaceutical sciences 2021-01, Vol.34 (1), p.135-141
Hauptverfasser:	Ikram, Huma, Atique, Iqra, Perveen, Shahla, Zakir, Rumaisa, Haleem, Darakhshan J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Anti-Anxiety Agents - administration & dosage Brain - drug effects Brain - metabolism Dopamine - metabolism Eating - drug effects Eating - physiology Eating - psychology Ethylenediaminetetraacetic acid Exploratory Behavior - drug effects Exploratory Behavior - physiology Lorazepam Lorazepam - administration & dosage Male Motor Activity - drug effects Motor Activity - physiology Physiological aspects Rats Rats, Wistar Serotonin - metabolism
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