TAK1 in the AP-1 pathway is a critical target of Saururus chinensis (Lour.) Baill in its anti-inflammatory action

Saururus chinensis (Lour.) Baill (Saururaceae), also known as Asian lizard's tail, is a plant commonly found in East Asia. Its leaves have been used in traditional medicine to treat many diseases such as edema, pneumonia, hypertension, leproma, jaundice, gonorrhea, and rheumatoid arthritis. Bas...

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Veröffentlicht in:	Journal of ethnopharmacology 2021-10, Vol.279, p.114400-114400, Article 114400
Hauptverfasser:	Zhang, Jianmei, Rho, Yangkook, Kim, Mi-Yeon, Cho, Jae Youl
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-inflammatory activity Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology AP-1 signaling pathway Cell Survival - drug effects Gene Expression Regulation - drug effects HEK293 Cells Humans MAP Kinase Kinase Kinases - genetics MAP Kinase Kinase Kinases - metabolism Mice Molecular Structure Nitric Oxide - metabolism Plant Extracts - chemistry Plant Extracts - pharmacology Plant Leaves - chemistry RAW 264.7 Cells RNA, Messenger - genetics RNA, Messenger - metabolism Saururus chinensis (Lour.) Baill (Saururaceae) TAK1 Transcription Factor AP-1 - genetics Transcription Factor AP-1 - metabolism
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