Protective role of cortistatin in pulmonary inflammation and fibrosis

Background and Purpose Acute lung injury (ALI), acute respiratory distress syndrome (ARDS) and pulmonary fibrosis remain major causes of morbidity, mortality and a healthcare burden in critically ill patient. There is an urgent need to identify factors causing susceptibility and for the design of ne...

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Veröffentlicht in:	British journal of pharmacology 2021-11, Vol.178 (21), p.4368-4388
Hauptverfasser:	Barriga, Margarita, Benitez, Raquel, Ferraz‐de‐Paula, Viviane, Garcia‐Frutos, Marina, Caro, Marta, Robledo, Gema, O'Valle, Francisco, Campos‐Salinas, Jenny, Delgado, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	acute lung injury Alveoli Animals Antagonists Bleomycin Disease Models, Animal Drug development Edema Fibroblasts Fibrosis Ghrelin Immunomodulation Inflammation Inflammation - drug therapy Inflammation - pathology Lipopolysaccharides Lung - pathology Lung diseases Macrophages Mice Morbidity Mortality neuropeptide Neuropeptides - pharmacology Phenotypes Pneumonia - chemically induced Pneumonia - drug therapy Pulmonary fibrosis pulmonary inflammation Respiratory distress syndrome Respiratory failure Severe acute respiratory syndrome coronavirus 2 Somatostatin
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