MiR-125b inhibits cardiomyocyte apoptosis by targeting BAK1 in heart failure

Although miR-125b plays a crucial role in many human cancers. However, its function in heart failure (HF) remains unclear. Our study aimed to investigate its involvement in heart failure. In this study, the mouse HF model was successfully constructed through transverse aortic constriction (TAC) oper...

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Veröffentlicht in:	Molecular Medicine 2021-07, Vol.27 (1), p.72-72, Article 72
Hauptverfasser:	Zhang, Bei, Mao, Shanyong, Liu, Xingde, Li, Sha, Zhou, Haiyan, Gu, Ying, Liu, Wupeng, Fu, Lei, Liao, Chunyan, Wang, Pengzhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Apoptosis Apoptosis - genetics BAK1 bcl-2 Homologous Antagonist-Killer Protein - genetics Cells, Cultured Disease Models, Animal Disease Susceptibility Gene Expression Regulation Heart Heart failure Heart Failure - diagnosis Heart Failure - etiology Heart Failure - metabolism Heart Function Tests Immunohistochemistry Male Mice MicroRNAs - genetics MiR-125b Myocytes, Cardiac - metabolism RNA RNA Interference Ultrasonography
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