Synthesis of C6-amino agarose and evaluation of its antibacterial activity

In this paper, the biologically inert agarose was selectively modified at C6 of β-d-Galp units to produce an amino derivative with antibacterial property. The synthetic route involved the preparation of tosyl and azido agarose intermediates. All the polysaccharide derivatives were characterized by m...

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Veröffentlicht in:	Carbohydrate research 2021-09, Vol.507, p.108387, Article 108387
Hauptverfasser:	Heuko, Janaina G., Duarte, Maria Eugênia R., Gonçalves, Alan G., Noseda, Miguel D., Murakami, Fabio S., de Carvalho, Mariana M., Ducatti, Diogo R.B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agarose Amino polysaccharide Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity Azido polysaccharide Escherichia coli - drug effects Galactan Microbial Sensitivity Tests Pseudomonas aeruginosa - drug effects Sepharose - chemistry Staphylococcus aureus - drug effects Tosylation
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