Mitophagy and apoptosis mediated by ROS participate in AlCl3-induced MC3T3-E1 cell dysfunction

Aluminum (Al), as a common environmental pollutant, causes osteoblast (OB) dysfunction and then leads to Al-related bone diseases (ARBD). One of the mechanisms of ARBD is oxidative stress, which leads to an increase in the production of reactive oxygen species (ROS). ROS can induce mitochondrial dam...

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Veröffentlicht in:Food and chemical toxicology 2021-09, Vol.155, p.112388-112388, Article 112388
Hauptverfasser: Liu, Menglin, Wu, Xia, Cui, Yilong, Liu, Pengli, Xiao, Bonan, Zhang, Xuliang, Zhang, Jian, Sun, Zhuo, Song, Miao, Shao, Bing, Li, Yanfei
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