Smarcd1 antagonizes the apoptosis of injured MES23.5 DA cells by enhancing the effect of Six2 on GDNF expression

•Smarcd1 was a cofactor interacting with Six2 in injured MES23.5 cells.•Smarcd1 enhanced the effect of Six2 on GDNF expression in injured MES23.5 cells.•Smarcd1 enhanced the anti-apoptotic effect of Six2 on injured MES23.5 cells. Glial cell line-derived neurotrophic factor (GDNF) played critical rol...

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Veröffentlicht in:	Neuroscience letters 2021-08, Vol.760, p.136088-136088, Article 136088
Hauptverfasser:	Gao, Jin, Qin, Deng-li, Tang, Chuan-xi, Kang, Xiao-yu, Song, Cheng-jie, Zhang, Can-tang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cell Line Dopaminergic (DA) cells Dopaminergic Neurons - metabolism Dopaminergic Neurons - pathology Gene Expression Regulation Glial cell line-derived neurotrophic factor (GDNF) Glial Cell Line-Derived Neurotrophic Factor - genetics Homeodomain Proteins - metabolism Hybrid Cells Mice Rats Six2 Smarcd1 Transcription Factors - metabolism
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