A natural product of acteoside ameliorate kidney injury in diabetes db/db mice and HK‐2 cells via regulating NADPH/oxidase‐TGF‐β/Smad signaling pathway

This study was designed to investigate the protective effects and mechanisms of acteoside on DKD in diabetes male db/db mice and high glucose‐induced HK‐2 cells. The diabetes db/db mice were divided randomly into model group, metformin group, irbesartan group, and acteoside group. We observed the na...

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Veröffentlicht in:Phytotherapy research 2021-09, Vol.35 (9), p.5227-5240
Hauptverfasser: Wang, Qinwen, Dai, Xinxin, Xiang, Xiang, Xu, Zhuo, Su, Shulan, Wei, Dandan, Zheng, Tianyao, Shang, Er‐xin, Qian, Dawei, Duan, Jin‐ao
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Sprache:eng
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