Immunofluorescence Analysis of NF-kB and iNOS Expression in Different Cell Populations during Early and Advanced Knee Osteoarthritis

Synovitis of the knee synovium is proven to be a precursor of knee osteoarthritis (OA), leading to a radiologically advanced stage of the disease. This study was conducted to elucidate the expression pattern of different inflammatory factors-NF-kB, iNOS, and MMP-9 in a subpopulation of synovial cell...

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Veröffentlicht in:	International journal of molecular sciences 2021-06, Vol.22 (12), p.6461, Article 6461
Hauptverfasser:	Ostojic, Marko, Zevrnja, Ante, Vukojevic, Katarina, Soljic, Violeta
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis Biochemistry & Molecular Biology Biomedical materials Cartilage CD5 antigen Chemistry Chemistry, Multidisciplinary Cytokines Endothelial cells Fibroblasts Gelatinase B Immunofluorescence inducible nitric oxide synthase Inflammation Knee Leukocytes Life Sciences & Biomedicine Localization Lymphocytes macrophage Macrophages Muscles NF-κB protein Nitric oxide Nitric-oxide synthase nuclear factor kappa B Osteoarthritis Physical Sciences Science & Technology Smooth muscle Synovial membrane Synovitis Synovium Vimentin
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