Dynamin-2 mediates clathrin-dependent endocytosis for amyloid-β internalization in brain microvascular endothelial cells

Dynamin is recognized as a crucial regulator for membrane fission and has three isoforms in mammals. But the expression patterns of dynamin isoforms and their roles in non-neuronal cells are incompletely understood. In this study, the expression profiles of dynamin isoforms and their roles in endocy...

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Veröffentlicht in:	Microvascular research 2021-11, Vol.138, p.104219-104219, Article 104219
Hauptverfasser:	Du, Shu-Song, Sun, Xue, Cen, Jie, Shi, Jun-Xiu, An, Ming-Xin, Zhao, Wei-Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid beta-Peptides - metabolism Aβ internalization Brain - blood supply Brain microvascular endothelial cells Cell Membrane - metabolism Cell Membrane - ultrastructure Cell Polarity Cells, Cultured Clathrin - metabolism Clathrin-Coated Vesicles - metabolism Clathrin-Coated Vesicles - ultrastructure Clathrin-dependent endocytosis Dynamin Dynamin II - genetics Dynamin II - metabolism Endocytosis Endothelial Cells - metabolism Endothelial Cells - ultrastructure Humans Microvessels - metabolism Time Factors Transferrin - metabolism
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