Activation of CRF1 receptors expressed in brainstem autonomic nuclei stimulates colonic enteric neurons and secreto‐motor function in male rats

Background Hypothalamic corticotropin‐releasing factor (CRF) receptor 1 (CRF1) plays a role in acute stress‐related stimulation of colonic motor function. Less is known on CRF1 signaling in the brainstem. Methods We investigate CRF1 expression in the brainstem and the colonic response to 4th ventric...

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Veröffentlicht in:	Neurogastroenterology and motility 2021-11, Vol.33 (11), p.e14189-n/a
Hauptverfasser:	Yuan, Pu‐Qing, Wu, S. Vincent, Stengel, Andreas, Sato, Ken, Taché, Yvette
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative splicing Area postrema Autonomic nervous system Brain stem brainstem colon CRF1 receptor isoforms c‐Fos Diarrhea Enteric nervous system Hypothalamus Immunoreactivity Locus coeruleus Medulla oblongata Motor nuclei Neurons pChAT Pons rat Rodents Solitary tract nucleus Urocortin urocortin 2 Ventricle Ventricles (cerebral)
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