A single amino acid variation of NV protein of viral hemorrhagic septicemia virus increases protein stability and decreases immune gene expression

Viral hemorrhagic septicemia virus (VHSV) causes severe mortality among more than 90 fish species. The 11 kb viral genome encodes six proteins including nonvirion protein (NV). In previous study, we reported that NV gene variations of VHSV decrease cellular energy metabolism. Among several NV mutant...

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Veröffentlicht in:Fish & shellfish immunology 2021-09, Vol.116, p.84-90
Hauptverfasser: Seong, Mi So, Jang, Eun Ah, Kim, Julan, Kim, Woo-Jin, Cheong, JaeHun
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Sprache:eng
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