The H2S-Donor Erucin Exhibits Protective Effects against Vascular Inflammation in Human Endothelial and Smooth Muscle Cells

Preservation of vascular wall integrity against degenerative processes associated with ageing, fat-rich diet and metabolic diseases is a timely therapeutical challenge. The loss of endothelial function and integrity leads to cardiovascular diseases and multiorgan inflammation. The protective effects...

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Veröffentlicht in:	Antioxidants 2021-06, Vol.10 (6), p.961, Article 961
Hauptverfasser:	Martelli, Alma, Piragine, Eugenia, Gorica, Era, Citi, Valentina, Testai, Lara, Pagnotta, Eleonora, Lazzeri, Luca, Pecchioni, Nicola, Ciccone, Valerio, Montanaro, Rosangela, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla, Brancaleone, Vincenzo, Morbidelli, Lucia, Calderone, Vincenzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Antibiotics Antioxidants Aqueous solutions Biochemistry & Molecular Biology Cadherins Cardiovascular diseases Caspase-3 Cell viability Chemistry, Medicinal Cyclooxygenase-2 Diabetes Endothelial cells endothelial permeability Eruca sativa Mill erucin Experiments Food Science & Technology Functional foods & nutraceuticals Glucose Growth factors H2S-donor Hydrogen sulfide Inflammation Interleukin 6 Isothiocyanate Life Sciences & Biomedicine Metabolic disorders Metabolism NF-κB protein Penicillin Permeability Pharmacology & Pharmacy Physiology Preservation Science & Technology Smooth muscle Tumor necrosis factor-α vascular inflammation Zonula occludens-1 protein
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