Crystal structure of clinically reported mutations Gly656Arg, Gly656Glu and Asp751His identified in the kinase domain of EphA7

Erythropoietin producing hepatocellular (Eph) forms the largest family of receptor tyrosine kinases (RTK). As a family, Eph regulates physiological events such as cell-cell interaction, cell migration, and adhesion. The Kinase domain is the catalytic core of the Eph receptor and is highly conserved...

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Veröffentlicht in:	Biochemical and biophysical research communications 2021-09, Vol.568, p.62-67
Hauptverfasser:	Chakraborty, Shubhashish, Varma, Ashok K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Crystal structure Erythropoietin producing hepatocellular (Eph) Mutations RTKs Structural alterations
Online-Zugang:	Volltext
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