Comparison of CD20 Binding Affinities of Rituximab Produced in Nicotiana benthamiana Leaves and Arabidopsis thaliana Callus

Plants are promising drug-production platforms with high economic efficiency, stability, and convenience in mass production. However, studies comparing the equivalency between the original antibodies and those produced in plants are limited. Amino acid sequences that constitute the Fab region of an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular biotechnology 2021-11, Vol.63 (11), p.1016-1029
Hauptverfasser:	Kang, Cho Eun, Lee, Seungeun, Seo, Dong Hye, Heo, Woon, Kwon, Sun Hyung, Kim, JeongRyeol, Lee, Jinu, Ko, Byoung Joon, Koiwa, Hisashi, Kim, Woo Taek, Kim, Joo Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Amino acids Animals Antibodies Antibody Affinity Antigens Antigens, CD20 - chemistry Antigens, CD20 - metabolism Antineoplastic Agents, Immunological - isolation & purification Antineoplastic Agents, Immunological - metabolism Arabidopsis - genetics Arabidopsis - metabolism Arabidopsis thaliana Binding Biochemistry Biological products Biological Techniques Biotechnology Callus CD20 antigen Cell Biology Chemistry Chemistry and Materials Science Cricetinae Cytotoxicity Drugs Efficiency Epitopes Human Genetics Humans Immunotherapy Leaves Light Lymphoma Mammals Mass production Monoclonal antibodies Nicotiana - genetics Nicotiana - metabolism Nicotiana benthamiana Non-Hodgkin's lymphoma Original Paper Peptides Pharmaceuticals Plant Leaves - chemistry Plant Leaves - metabolism Plant species Post-transcription Protein Science Proteins Recombinant Proteins - biosynthesis Recombinant Proteins - genetics Recombinant Proteins - isolation & purification Rituximab Rituximab - biosynthesis Rituximab - genetics Rituximab - isolation & purification Rituximab - metabolism Science Targeted cancer therapy Tobacco
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!