Up-down regulation of HIF-1α in cancer progression

•HIF-1α stimulate cancer progression through angiogenesis, metastasis, cell proliferation and metabolism alternation process.•HIF-1α has important role during cancer progression through simulation of genetic instability.•Inhibition of HIF-1α has promising result in cancer treatment. Hypoxia induicib...

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Veröffentlicht in:	Gene 2021-09, Vol.798, p.145796-145796, Article 145796
Hauptverfasser:	Rashid, Mohsen, Zadeh, Leila Rostami, Baradaran, Behzad, Molavi, Ommoleila, Ghesmati, Zeinab, Sabzichi, Mehdi, Ramezani, Fatemeh
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer progression Cancer stem cells Drug resistance HIF-1α Invasion and metastasis Proliferation and apoptosis
Online-Zugang:	Volltext
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