Lithocholic acid-tryptophan conjugate (UniPR126) based mixed micelle as a nano carrier for specific delivery of niclosamide to prostate cancer via EphA2 receptor

UniPR126 based nano micelle has carried niclosamide to prostate cancer via EphA2 by enhancing its cellular uptake and ensuring a synergistic killing by interfering with EphA2 and Wnt signaling. [Display omitted] Targeted delivery of chemotherapeutic agents is considered a prominent strategy for the...

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Veröffentlicht in:	International journal of pharmaceutics 2021-08, Vol.605, p.120819-120819, Article 120819
Hauptverfasser:	Jannu, Arun Kumar, Puppala, Eswara Rao, Gawali, Basveshwar, Syamprasad, N.P., Alexander, Amit, Marepally, Srujan, Chella, Naveen, Gangasani, Jagadeesh Kumar, Naidu, V.G.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile acid Drug repurpose Ephrin type-A receptor 2 Targeted delivery Wnt signalling
Online-Zugang:	Volltext
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