Acidity‐Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer

Immunotherapy shows promising therapeutic potential for long‐term tumor regression. However, current cancer immunotherapy displays a low response rate due to insufficient immunogenicity of the tumor cells. To address these challenges, herein, intracellular‐acidity‐activatable dynamic nanoparticles f...

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Veröffentlicht in:	Advanced materials (Weinheim) 2021-08, Vol.33 (31), p.e2101155-n/a
Hauptverfasser:	Song, Rundi, Li, Tianliang, Ye, Jiayi, Sun, Fang, Hou, Bo, Saeed, Madiha, Gao, Jing, Wang, Yingjie, Zhu, Qiwen, Xu, Zhiai, Yu, Haijun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Block copolymers Cancer cancer immunotherapy Cell death Cell Line, Tumor Chemical bonds Covalent bonds ferroptosis Ferroptosis - drug effects Glutathione Humans Hydrogen-Ion Concentration immune resistance immunogenic cell death Immunotherapy Interferon Lymphocytes Materials science Mice Nanoparticles Nanoparticles - chemistry Peroxidase Photochemotherapy - methods Photodynamic therapy Protonation T lymphocytes Tumors
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