Hyperkyphosis is not dependent on bone mass and quality in the mouse model of Marfan syndrome

Marfan syndrome (MFS) is an autosomal dominant disease affecting cardiovascular, ocular and skeletal systems. It is caused by mutations in the fibrillin-1 (FBN1) gene, leading to structural defects of connective tissue and increased activation of TGF-β. Angiotensin II (ang-II) is involved in TGF-β a...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2021-11, Vol.152, p.116073-116073, Article 116073
Hauptverfasser:	Souza, Rodrigo Barbosa de, Kawahara, Elisa Ito, Farinha-Arcieri, Luis Ernesto, Gyuricza, Isabela Gerdes, Neofiti-Papi, Bianca, Miranda-Rodrigues, Manuela, Teixeira, Marilia Bianca Cruz Grecco, Fernandes, Gustavo Ribeiro, Lemes, Renan Barbosa, Reinhardt, Dieter P., Gouveia, Cecília Helena, Pereira, Lygia V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone mass Hyperkyphosis Marfan syndrome Spine defect anterior longitudinal ligament
Online-Zugang:	Volltext
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