Comment on “comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian women” by Saleh et al
•Alterations to the somatic genome lead to a tumor.•Different germ line genomes influence the formation of the tumor and its response to therapeutics.•Germ line genetics can play a role in breast cancer.•Race is an imperfect measure of germ line genetics.•Black women have a higher incidence of tripl...
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| Veröffentlicht in: | Translational oncology 2021-09, Vol.14 (9), p.101164-101164, Article 101164 |
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| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | •Alterations to the somatic genome lead to a tumor.•Different germ line genomes influence the formation of the tumor and its response to therapeutics.•Germ line genetics can play a role in breast cancer.•Race is an imperfect measure of germ line genetics.•Black women have a higher incidence of triple negative breast cancer. |
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| ISSN: | 1936-5233 1936-5233 |
| DOI: | 10.1016/j.tranon.2021.101164 |