Diagnostic and Prognostic Significance of Keap1 mRNA Expression for Lung Cancer Based on Microarray and Clinical Information from Oncomine Database

Summary We performed a bioinformatics analysis with validation by multiple databases, aiming to evaluate the diagnostic and prognostic value of Kelch-like ECH-associated protein 1 (Keap1) mRNA for lung cancer, and to explore possible mechanisms. Diagnostic performance of Keap1 mRNA was determined by...

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Veröffentlicht in:	Current medical science 2021-06, Vol.41 (3), p.597-609
Hauptverfasser:	Liu, Guang-ya, Zhang, Wei, Chen, Xu-chi, Wu, Wen-juan, Wan, Shi-qian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma of Lung - diagnosis Adenocarcinoma of Lung - genetics Adenocarcinoma of Lung - pathology Biomarkers, Tumor - genetics Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - pathology Computational Biology Female Gene Expression Regulation, Neoplastic - genetics Humans Kaplan-Meier Estimate Kelch-Like ECH-Associated Protein 1 - genetics Male Medicine Medicine & Public Health Microarray Analysis NF-E2-Related Factor 2 - genetics Progression-Free Survival Proportional Hazards Models RNA, Messenger - genetics
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