Fluorescent nanoparticle‐mediated semiquantitative MYC protein expression analysis in morphologically diffuse large B‐cell lymphoma

The current World Health Organization (WHO) classification defines a new disease entity of high‐grade B‐cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements, making fluorescence in situ hybridization (FISH) screening for these genes mandatory. In addition, the prognostic significance of MYC ex...

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Veröffentlicht in:	Pathology international 2021-09, Vol.71 (9), p.594-603
Hauptverfasser:	Takayanagi, Natsuko, Momose, Shuji, Kikuchi, Jun, Tanaka, Yuka, Anan, Tomoe, Yamashita, Takahisa, Higashi, Morihiro, Tokuhira, Michihide, Kizaki, Masahiro, Tamaru, Jun‐ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	3,3'-Diaminobenzidine - chemistry Adult Aged B-cell lymphoma Bcl-6 protein diffuse large B‐cell lymphoma Evaluation Female Fluorescence Fluorescence in situ hybridization fluorescent nanoparticles Gene Rearrangement high grade B‐cell lymphoma Humans Immunohistochemistry In Situ Hybridization, Fluorescence Luminescent Agents - chemistry Lymphoma Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - pathology Male Middle Aged MYC Myc protein Nanoparticles Nanoparticles - chemistry Phosphors phosphor‐integrated dots PID Prognosis Protein expression Proteins Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism Young Adult
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