Detection of azole resistance in Aspergillus fumigatus complex isolates using MALDI-TOF mass spectrometry

The main goal of this study was to accurately detect azole resistance in species of the Aspergillus fumigatus complex by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Identification of isolates (n = 868) was done with MALDI-TOF MS using both commercial...

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Veröffentlicht in:	Clinical microbiology and infection 2022-02, Vol.28 (2), p.260-266
Hauptverfasser:	Zvezdanova, Margarita Estreya, Arroyo, Manuel J., Méndez, Gema, Candela, Ana, Mancera, Luis, Rodríguez, Julio García, Serra, Julia Lozano, Jiménez, Rosa, Lozano, Inmaculada, Castro, Carmen, López, Concepción, Muñoz, Patricia, Guinea, Jesús, Escribano, Pilar, Rodríguez-Sánchez, Belén, Sánchez-Yebra, Waldo, Sánchez-Gómez, Juan, Marfil, Eduardo, Muñoz de la Rosa, Montserrat, García, Rocío Tejero, Cobo, Fernando, Rezusta, Antonio, Peláez, Teresa, Castelló-Abietar, Cristian, Costales, Isabel, Echeverría, Cristina Labayru, Pérez, Cristina Losa, Megías-Lobón, Gregoria, Lorenzo, Belén, Sánchez-Reus, Ferrán, Ayats, Josefina, Martín, María Teresa, Vidal, Inmaculada, Sánchez-Hellín, Victoria, Ibáñez, Elisa, Pemán, Javier, Fajardo, Miguel, Pazos, Carmen, Rodríguez-Mayo, María, Pérez-Ayala, Ana, Gómez, Elia, Serrano, Julia, Reigadas, Elena, Rodríguez, Belén, Zvezdanova, Estreya, Díaz-García, Judith, Gómez-Núñez, Ana, Leiva, José González, Machado, Marina, Sánchez-Romero, Isabel, García-Rodríguez, Julio, Luis del Pozo, José, Vallejo, Manuel Rubio, Ruiz de Alegría-Puig, Carlos, López-Soria, Leyre, Marimón, José María, Vicente, Diego, Fernández-Torres, Marina, Hernáez-Crespo, Silvia
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal Agents - pharmacology Antifungal Agents - therapeutic use Aspergillus fumigatus - genetics Aspergillus fumigatus complex Azole resistance Azoles - pharmacology Drug Resistance, Fungal Humans MALDI-TOF Mass spectrometry Microbial Sensitivity Tests Peak analysis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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