PKCε controls the fusion of secretory vesicles in mast cells in a phosphatidic acid-dependent mode

PKCε is highly expressed in mast cells and plays a fundamental role in the antigen-triggered activation of the allergic reaction. Although its regulation by diacylglycerols has been described, its regulation by acidic phospholipids and how this regulation leads to the control of downstream vesicle s...

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Veröffentlicht in:	International journal of biological macromolecules 2021-08, Vol.185, p.377-389
Hauptverfasser:	Serrano-López, Emilio M., López-Martínez, David, Gómez-Fernández, Juan C., Egea-Jiménez, Antonio Luis, Corbalán-García, Senena
Format:	Artikel
Sprache:	eng
Schlagworte:	C1 domain Diacylglycerol Phosphatidic acid PKC SNARE
Online-Zugang:	Volltext
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