Arthritis and enthesitis in the hip and pelvis region in spondyloarthritis - OMERACT validation of two whole-body MRI methods

To validate reliability, correlation and responsiveness of two whole-body MRI scores for the hip/pelvis region in spondyloarthritis. Assessment of hip/pelvis inflammation in 4 multi-reader exercises using the OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE)...

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Veröffentlicht in:Seminars in arthritis and rheumatism 2021-08, Vol.51 (4), p.940-945
Hauptverfasser: Wetterslev, Marie, Lambert, Robert GW, Maksymowych, Walter P, Eshed, Iris, Pedersen, Susanne J, Bird, Paul, Stoenoiu, Maria S, Krabbe, Simon, Mathew, Ashish J, Foltz, Violaine, Gandjbakhch, Frédérique, Paschke, Joel, De Marco, Gabriele, Marzo-Ortega, Helena, Carron, Philippe, Poulsen, Anna EF, Jaremko, Jacob L, Conaghan, Philip G, Østergaard, Mikkel
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container_end_page 945
container_issue 4
container_start_page 940
container_title Seminars in arthritis and rheumatism
container_volume 51
creator Wetterslev, Marie
Lambert, Robert GW
Maksymowych, Walter P
Eshed, Iris
Pedersen, Susanne J
Bird, Paul
Stoenoiu, Maria S
Krabbe, Simon
Mathew, Ashish J
Foltz, Violaine
Gandjbakhch, Frédérique
Paschke, Joel
De Marco, Gabriele
Marzo-Ortega, Helena
Carron, Philippe
Poulsen, Anna EF
Jaremko, Jacob L
Conaghan, Philip G
Østergaard, Mikkel
description To validate reliability, correlation and responsiveness of two whole-body MRI scores for the hip/pelvis region in spondyloarthritis. Assessment of hip/pelvis inflammation in 4 multi-reader exercises using the OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Hip Inflammation Magnetic Resonance Imaging Scoring System (HIMRISS). In exercises 3–4 (11/20 cases, respectively; 9 readers) reliability was mostly good for the 3 best calibrated readers. Median pairwise single-measure ICC for status were 0.58–0.65 (WIPE-osteitis), 0.10–0.88 (HIMRISS-osteitis) and for status/change 0.38–0.72/0.52–0.60 (WIPE-synovitis/effusion) and 0.68–0.89/0.78–0.85 (HIMRISS-synovitis/effusion). SRM was 1.23 for WIPE-osteitis, while lower for WIPE-synovitis/effusion and HIMRISS. MRI-WIPE and HIMRISS may after further validation be useful in future spondyloarthritis trials.
doi_str_mv 10.1016/j.semarthrit.2021.05.006
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subjects HIMRISS
Hip
MRI-WIPE
OMERACT
Spondyloarthritis
Whole-body MRI
title Arthritis and enthesitis in the hip and pelvis region in spondyloarthritis - OMERACT validation of two whole-body MRI methods
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