Polymerized vorinostat mediated photodynamic therapy using lysosomal spatiotemporal synchronized drug release complex

[Display omitted] •Combining photosensitizers and histone deacetylase inhibitor potentiate oncotherapy.•Polymerized vorinostat loading photosensitizer synchronized release drugs.•It significantly suppress tumor growth and pulmonary metastasis in mice.•It reveals a promising prospect to inhibit tumor...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2021-09, Vol.205, p.111903-111903, Article 111903
Hauptverfasser:	Hu, Pengwei, Sun, Miao, Lu, Fengkun, Wang, Sizhen, Hou, Lei, Yu, Yingjie, Zhang, Yunchang, Sun, Linhong, Yao, Jianzhong, Yang, Feng, Wang, Chen, Ma, Zhiqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	HDAC inhibitor Photodynamic therapy Polymerized HDACis prodrug Spatiotemporal synchronized drug release
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!