Mechanism, specificity, and function of FANCD2‐FANCI ubiquitination and deubiquitination

Fanconi anemia (FA) is a rare genetic disorder caused by mutations in any of the currently 22 known FA genes. The products of these genes, along with other FA‐associated proteins, participate in a biochemical pathway, known as the FA pathway. This pathway is responsible for the repair of DNA interst...

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Veröffentlicht in:The FEBS journal 2022-08, Vol.289 (16), p.4811-4829
Hauptverfasser: Lemonidis, Kimon, Arkinson, Connor, Rennie, Martin L., Walden, Helen
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Sprache:eng
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