Sleep/wake cycle alterations as a cause of neurodegenerative diseases: A Mendelian randomization study

•Plausible causality exists between sleep/wake patterns and neurodegenerative diseases.•Morning chronotype is potentially a delayer of the Parkinson’s age at onset.•Sleep efficiency could be causally associated with a lower risk of Alzheimer disease.•Daytime sleepiness could be altering amyotrophic...

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