Levels of Trimethylamine N-Oxide Remain Elevated Long Term After Left Ventricular Assist Device and Heart Transplantation and Are Independent From Measures of Inflammation and Gut Dysbiosis

BACKGROUNDTrimethylamine N-oxide (TMAO)-a gut-derived metabolite-is elevated in heart failure (HF) and linked to poor prognosis. We investigated variations in TMAO in HF, left ventricular assist device (LVAD), and heart transplant (HT) and assessed its relation with inflammation, endotoxemia, oxidat...

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Veröffentlicht in:Circulation. Heart failure 2021-06, Vol.14 (6), p.e007909-e007909
Hauptverfasser: Yuzefpolskaya, Melana, Bohn, Bruno, Javaid, Azka, Mondellini, Giulio M., Braghieri, Lorenzo, Pinsino, Alberto, Onat, Duygu, Cagliostro, Barbara, Kim, Andrea, Takeda, Koji, Naka, Yoshifumi, Farr, Maryjane, Sayer, Gabriel T., Uriel, Nir, Nandakumar, Renu, Mohan, Sumit, Colombo, Paolo C., Demmer, Ryan T.
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Sprache:eng
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