Nonlesional diffusely abnormal appearing white matter in clinically isolated syndrome: Prevalence, association with clinical and MRI features, and risk for conversion to multiple sclerosis

Background and Purpose While diffusely abnormal white matter (DAWM) is a nonlesional MRI abnormality identified in ∼25% of patients with multiple sclerosis (MS), it has yet to be investigated in patients at an earlier disease stage, namely clinically isolated syndrome (CIS). The goals of this study...

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Veröffentlicht in:	Journal of neuroimaging 2021-09, Vol.31 (5), p.981-994
Hauptverfasser:	Holmes, R. Davis, Vavasour, Irene M., Greenfield, Jamie, Zhao, Guojun, Lee, Jimmy S., Moore, G. R. Wayne, Tam, Roger, Metz, Luanne M., Trablousee, Anthony, Li, David K. B., Laule, Cornelia
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain stem clinically isolated syndrome Conversion Corticoids Corticosteroids diffusely abnormal white matter Magnetic resonance imaging Multiple sclerosis Neuroimaging Patients Risk Substantia alba
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