EGFR Exon 20 Insertion Mutations: Clinicopathological Characteristics and Treatment Outcomes in Advanced Non–Small Cell Lung Cancer

•EGFR exon 20 insertions are uncommon in non-small cell lung cancer.•Patient demographics and clinical features are similar to common EGFR mutations.•Platinum-based chemotherapy is the standard of care in advanced disease.•There is resistance to standard tyrosine kinase inhibitors, including osimert...

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Veröffentlicht in:Clinical lung cancer 2021-11, Vol.22 (6), p.e859-e869
Hauptverfasser: Leal, Jose Luis, Alexander, Marliese, Itchins, Malinda, Wright, Gavin M., Kao, Steven, Hughes, Brett G.M., Pavlakis, Nick, Clarke, Stephen, Gill, Anthony J, Ainsworth, Hannah, Solomon, Benjamin, John, Thomas
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Sprache:eng
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