Palliative Radiotherapy for Diffuse Large B-cell Lymphoma
Recent improvements in chemoimmunotherapies, targeted agents, hematopoietic stem cell transplants, and cellular therapies have revolutionized treatment paradigms for patients with diffuse large B-cell lymphoma (DLBCL). Even in the relapsed or refractory setting, contemporary treatment options are de...
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| Veröffentlicht in: | Clinical lymphoma, myeloma and leukemia myeloma and leukemia, 2021-10, Vol.21 (10), p.650-658 |
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| container_end_page | 658 |
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| container_title | Clinical lymphoma, myeloma and leukemia |
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| creator | Wright, Christopher M. Koroulakis, Antony I. Baron, Jonathan A. Chong, Elise A. Tseng, Yolanda D. Kurtz, Goldie LaRiviere, Michael Venigalla, Sriram Jones, Joshua A. Maity, Amit Mohindra, Pranshu Plastaras, John P. Paydar, Ima |
| description | Recent improvements in chemoimmunotherapies, targeted agents, hematopoietic stem cell transplants, and cellular therapies have revolutionized treatment paradigms for patients with diffuse large B-cell lymphoma (DLBCL). Even in the relapsed or refractory setting, contemporary treatment options are delivered with curative intent and can lead to lasting remissions. Although such therapies have improved overall outcomes, they have increasingly led to a wide variety of presentations of recurrent tumors in need of palliation. Here, we review the use of radiotherapy (RT) in the palliation of DLBCL. We draw particular attention to the evolving role for hypofractionated RT and low-dose RT for DLBCL. We review the available literature on these topics and focus on commonly encountered clinical scenarios. |
| doi_str_mv | 10.1016/j.clml.2021.05.007 |
| format | Article |
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Even in the relapsed or refractory setting, contemporary treatment options are delivered with curative intent and can lead to lasting remissions. Although such therapies have improved overall outcomes, they have increasingly led to a wide variety of presentations of recurrent tumors in need of palliation. Here, we review the use of radiotherapy (RT) in the palliation of DLBCL. We draw particular attention to the evolving role for hypofractionated RT and low-dose RT for DLBCL. 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Published by Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-913a3b13d6738974cb86919fb3b9c136a7d57e9c67e54efe0ab506c78765470a3</citedby><cites>FETCH-LOGICAL-c356t-913a3b13d6738974cb86919fb3b9c136a7d57e9c67e54efe0ab506c78765470a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.clml.2021.05.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34127417$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wright, Christopher M.</creatorcontrib><creatorcontrib>Koroulakis, Antony I.</creatorcontrib><creatorcontrib>Baron, Jonathan A.</creatorcontrib><creatorcontrib>Chong, Elise A.</creatorcontrib><creatorcontrib>Tseng, Yolanda D.</creatorcontrib><creatorcontrib>Kurtz, Goldie</creatorcontrib><creatorcontrib>LaRiviere, Michael</creatorcontrib><creatorcontrib>Venigalla, Sriram</creatorcontrib><creatorcontrib>Jones, Joshua A.</creatorcontrib><creatorcontrib>Maity, Amit</creatorcontrib><creatorcontrib>Mohindra, Pranshu</creatorcontrib><creatorcontrib>Plastaras, John P.</creatorcontrib><creatorcontrib>Paydar, Ima</creatorcontrib><title>Palliative Radiotherapy for Diffuse Large B-cell Lymphoma</title><title>Clinical lymphoma, myeloma and leukemia</title><addtitle>Clin Lymphoma Myeloma Leuk</addtitle><description>Recent improvements in chemoimmunotherapies, targeted agents, hematopoietic stem cell transplants, and cellular therapies have revolutionized treatment paradigms for patients with diffuse large B-cell lymphoma (DLBCL). 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| ispartof | Clinical lymphoma, myeloma and leukemia, 2021-10, Vol.21 (10), p.650-658 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Diffuse large B-cell lymphoma Humans Lymphoma Lymphoma, Large B-Cell, Diffuse - mortality Lymphoma, Large B-Cell, Diffuse - radiotherapy Palliation Palliative Care - methods Palliative radiotherapy Progression-Free Survival Radiotherapy |
| title | Palliative Radiotherapy for Diffuse Large B-cell Lymphoma |
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