Maternal methionine supplementation in mice affects long-term body weight and locomotor activity of adult female offspring

Methionine is a precursor of s-adenosylmethionine, the main donor of methyl radicals for methylation of DNA and other compounds. Previous studies have shown that reduced availability of methyl radicals during pregnancy/lactation decreased offspring perigonadal white adipose tissue (PWAT) and body we...

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Veröffentlicht in:	British journal of nutrition 2022-04, Vol.127 (8), p.1143-1152
Hauptverfasser:	Cavalcante-Silva, Vanessa, Ribeiro da Silva Vallim, Julia, Fernandes, Leandro, de Oliveira, Allan Chiaratti, D’Almeida, Vânia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosylmethionine Adipose tissue Animals Availability Birth weight Blood Body composition Body fat Body Weight Developmental Biology Dietary Supplements DNA methylation Female Females Homocysteine Laboratory animals Lactation Locomotion Locomotor activity Male Males Methionine Methionine - pharmacology Methyl radicals Mice Nutrition research Offspring Plasma Pregnancy Radicals S-Adenosylmethionine Sperm Supplements Vitamin B Vitamin deficiency
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