Metagenomic analysis of gut microbiota reveals its role in trimethylamine metabolism in heart failure

We had previously reported an increase in trimethylamine N-oxide (TMAO) levels in patients with both compensated and decompensated heart failure (HF) and alteration in gut microbiota composition using 16S rRNA gene amplicon analysis. Although a metagenome-wide analysis showed that choline-TMA lyase...

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Veröffentlicht in:	International journal of cardiology 2021-09, Vol.338, p.138-142
Hauptverfasser:	Emoto, Takuo, Hayashi, Tomohiro, Tabata, Tokiko, Yamashita, Tomoya, Watanabe, Hikaru, Takahashi, Tomoya, Gotoh, Yasuhiro, Kami, Kenjiro, Yoshida, Naofumi, Saito, Yoshihiro, Tanaka, Hidekazu, Matsumoto, Kensuke, Hayashi, Tetsuya, Yamada, Takuji, Hirata, Ken-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	A metagenome-wide shotgun sequencing analysis Gut microbiota Heart failure TMAO
Online-Zugang:	Volltext
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