From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics

•Understanding of how genotypes map onto molecular phenotypes and organismal functions is partial.•The networked organization of genotype-phenotype (GP) maps conditions evolution and adaptation.•Several topological properties of genotype spaces are universal.•The evolution of GP maps (not on GP maps...

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Veröffentlicht in:	Physics of life reviews 2021-09, Vol.38, p.55-106
Hauptverfasser:	Manrubia, Susanna, Cuesta, José A., Aguirre, Jacobo, Ahnert, Sebastian E., Altenberg, Lee, Cano, Alejandro V., Catalán, Pablo, Diaz-Uriarte, Ramon, Elena, Santiago F., García-Martín, Juan Antonio, Hogeweg, Paulien, Khatri, Bhavin S., Krug, Joachim, Louis, Ard A., Martin, Nora S., Payne, Joshua L., Tarnowski, Matthew J., Weiß, Marcel
Format:	Artikel
Sprache:	eng
Schlagworte:	Experimental evolution Fitness landscape Genotype Genotype network Genotype-phenotype map Molecular evolution Phenotype Phenotypic bias
Online-Zugang:	Volltext
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