An insight into lung cancer: a comprehensive review exploring ALK TKI and mechanisms of resistance

Implementation of precision medicine in lung cancer has benefited from intense research in the past years, developing subsequently an improved quality of life and increased overall survival of the patients. Targeted therapy has become one of the most important therapeutic innovations for the non-sma...

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Veröffentlicht in:	Biomolecules & biomedicine 2022-02, Vol.22 (1), p.1-13
Hauptverfasser:	Patcas, Adela, Chis, Ana Florica, Militaru, Claudia Florentina, Bordea, Ioana Roxana, Rajnoveanu, Ruxandra, Coza, Ovidiu Florin, Hanna, Reem, Tiberiu, Tamas, Todea, Doina Adina
Format:	Artikel
Sprache:	eng
Schlagworte:	ALK anaplastic lymphoma kinase Anaplastic Lymphoma Kinase - genetics Antineoplastic Agents - pharmacology Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Drug Resistance, Neoplasm - genetics Humans Lung Neoplasms - drug therapy Lung Neoplasms - genetics Lung Neoplasms - pathology NSCLC Protein Kinase Inhibitors - pharmacology Protein Kinase Inhibitors - therapeutic use Protein-Tyrosine Kinases - therapeutic use Quality of Life Receptor Protein-Tyrosine Kinases - genetics Receptor Protein-Tyrosine Kinases - therapeutic use resistance mechanisms TKI tyrosine kinase inhibitors
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