Role of extracellular vesicles in liver diseases and their therapeutic potential

[Display omitted] •Injured cells release pathological extracellular vesicles (EVs).•Pathological EVs contain miRNAs, proteins, phospholipids and DNA.•Targeting EV release or use of bioengineered EVs represent therapeutic strategies. More than eight hundred million people worldwide have chronic liver...

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Veröffentlicht in:	Advanced drug delivery reviews 2021-08, Vol.175, p.113816-113816, Article 113816
Hauptverfasser:	Kostallari, Enis, Valainathan, Shantha, Biquard, Louise, Shah, Vijay H., Rautou, Pierre-Emmanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cholestasis - drug therapy Cholestasis - pathology Cirrhosis Exosomes Extracellular Vesicles - drug effects Extracellular Vesicles - pathology Fibrosis Hepatitis, Viral, Human - drug therapy Hepatitis, Viral, Human - pathology Humans Liver Cirrhosis - drug therapy Liver Cirrhosis - pathology Liver Diseases - drug therapy Liver Diseases - pathology Liver Diseases, Alcoholic - drug therapy Liver Diseases, Alcoholic - pathology Microvesicles Portal hypertension Steatosis
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