Nicotinamide N-Methyltransferase in Acquisition of Stem Cell Properties and Therapy Resistance in Cancer

The activity of nicotinamide N-methyltransferase (NNMT) is tightly linked to the maintenance of the nicotinamide adenine dinucleotide (NAD(+)) level. This enzyme catalyzes methylation of nicotinamide (NAM) into methyl nicotinamide (MNAM), which is either excreted or further metabolized to N1-methyl-...

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Veröffentlicht in:	International journal of molecular sciences 2021-05, Vol.22 (11), p.5681, Article 5681
Hauptverfasser:	Kujundzic, Renata Novak, Prpic, Marin, Dakovic, Nikola, Dabelic, Nina, Tomljanovic, Marko, Mojzes, Anamarija, Frobe, Ana, Troselj, Koraljka Gall
Format:	Artikel
Sprache:	eng
Schlagworte:	aldehyde oxidase Biochemistry & Molecular Biology cancer Chemistry Chemistry, Multidisciplinary epigenetic reprogramming Life Sciences & Biomedicine nicotinamide adenine dinucleotide nicotinamide N-methyltransferase Physical Sciences Review Science & Technology senescence
Online-Zugang:	Volltext
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