Maturation of human pluripotent stem cell derived cardiomyocytes in vitro and in vivo

Human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) represent an inexhaustible cell source for in vitro disease modeling, drug discovery and toxicity screening, and potential therapeutic applications. However, currently available differentiation protocols yield populations of hPSC-CMs with...

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Veröffentlicht in:	Seminars in cell & developmental biology 2021-10, Vol.118, p.163-171
Hauptverfasser:	Gomez-Garcia, M. Juliana, Quesnel, Elya, Al-attar, Rasha, Laskary, Andrew R., Laflamme, Michael A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiomyocyte Cell Differentiation Developmental biology Human pluripotent stem cell Humans Maturation Myocytes, Cardiac - metabolism Pluripotent Stem Cells - metabolism
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