Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile

Mendelian randomization studies have shown that triglyceride (TG)- lowering lipoprotein lipase (LPL) alleles and low-density lipoprotein-cholesterol (LDL-C)-lowering alleles have independent beneficial associations on cardiovascular disease (CVD) risk. We aimed to provide further insight into this o...

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Veröffentlicht in:	Atherosclerosis 2021-07, Vol.328, p.144-152
Hauptverfasser:	Ibi, Dorina, Blauw, Lisanne L., Noordam, Raymond, Dollé, Martijn E.T., Jukema, J. Wouter, Rosendaal, Frits R., Christodoulides, Constantinos, Neville, Matt J., Koivula, Robert, Rensen, Patrick C.N., Karpe, Fredrik, van Dijk, Ko Willems
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiovascular disease LDL-Cholesterol-lowering Lipoprotein lipase Mendelian randomization Metabolomics Triglyceride-lowering
Online-Zugang:	Volltext
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