Interleukin 19 suppresses RANKL-induced osteoclastogenesis via the inhibition of NF-κB and p38MAPK activation and c-Fos expression in RAW264.7 cells

Interleukin 19 (IL-19) is a member of the IL-10 family of cytokines and is known as an inhibitory cytokine. IL-10, also an inhibitory cytokine, suppresses the receptor activator of nuclear factor κB (NF-κB) ligand (RANKL)-induced osteoclast differentiation. However, the effects of IL-19 on osteoclas...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2021-08, Vol.144, p.155591-155591, Article 155591
Hauptverfasser:	Tsubaki, Masanobu, Takeda, Tomoya, Matsuda, Takuya, Yamamoto, Yuuta, Higashinaka, Aki, Yamamoto, Kasane, Tsurushima, Katsumasa, Ishizaka, Toshihiko, Nishida, Shozo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone Marrow Cells - metabolism c-Fos Cell Differentiation - physiology Cell Line Interleukin 19 Interleukins - metabolism Macrophages - metabolism Mice Monocytes - metabolism NF-kappa B - metabolism NF-κB Osteoclast differentiation Osteoclasts - metabolism Osteogenesis - physiology p38 Mitogen-Activated Protein Kinases - metabolism p38MAPK Proto-Oncogene Proteins c-fos - metabolism RANK Ligand - metabolism RAW 264.7 Cells Signal Transduction - physiology
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