Allergen‐specific IgG show distinct patterns in persistent and transient food allergy

Background Immediate food‐allergic reactions are IgE‐mediated, but many individuals with detectable allergen‐specific IgE do not react to the food. Allergen‐specific IgG may interfere with allergen‐IgE interaction and/or through intracellular inhibitory signalling to suppress mast cell and basophil...

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Veröffentlicht in:	Pediatric allergy and immunology 2021-10, Vol.32 (7), p.1508-1518
Hauptverfasser:	McKendry, Richard T., Kwok, Matthew, Hemmings, Oliver, James, Louisa K., Santos, Alexandra F., Sampson, Hugh
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens Animals basophil Basophils Cattle Cell activation Children Cow's milk egg Enzyme-linked immunosorbent assay FcγRIIβ Female Flow cytometry Food allergies food allergy Food Hypersensitivity Humans Hypersensitivity (immediate) IgE IgG Immunoglobulin A Immunoglobulin E Immunoglobulin G Intracellular signalling Isotypes Leukocytes (basophilic) mast cell Mast cells Milk Hypersensitivity peanut tolerance
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