Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis

The prognosis of elderly individuals with idiopathic pulmonary fibrosis (IPF) remains poor. Fibroblastic foci, in which aggregates of proliferating fibroblasts and myofibroblasts are involved, are the pathological hallmark lesions in IPF to represent focal areas of active fibrogenesis. Fibroblast he...

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Veröffentlicht in:	The European respiratory journal 2021-12, Vol.58 (6), p.2003397
Hauptverfasser:	Nakahara, Yoshio, Hashimoto, Naozumi, Sakamoto, Koji, Enomoto, Atsushi, Adams, Taylor S, Yokoi, Toyoharu, Omote, Norihito, Poli, Sergio, Ando, Akira, Wakahara, Keiko, Suzuki, Atsushi, Inoue, Masahide, Hara, Akitoshi, Mizutani, Yasuyuki, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Rosas, Ivan O, Takahashi, Masahide, Kaminski, Naftali, Hasegawa, Yoshinori
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Bleomycin Fibroblasts - pathology Fibrosis Humans Idiopathic Pulmonary Fibrosis - pathology Lung - pathology Mice Senescence-Associated Secretory Phenotype
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